Association of platelet and hematocrit value with arteriovenous fistula (AVF) failure in hemodialysis patient at Bali Husada Cipta Canti, Bali, Indonesia
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Keywords
Arteriovenous fistula, arteriovenous fistula failure, A stuck hemodialysis catheter
Abstract
Introduction: Hemodialysis is one of the renal replacement therapies used for end-stage renal disease (ESRD) patients. Arteriovenous fistula (AVF) is the preferred hemodialysis access type because it has better patency rates and fewer complications than other access types. However, around 31-61% of AVF fail to mature. An early AVF failure may be due to a lack of maturation or thrombosis, and late failure defines as a failure after successful use. Some factors that make AVF fail are injury of the endothelial wall or hypercoagulation. This study aimed to determine the association between pre-operative platelet and hematocrit value with AVF failure in BHCC Clinic Denpasar.
Method: This is an analytic cross-sectional study. The data were collected from medical records from all dialytic patients from January 2020-December 2020. Patients with inclusion criteria were collected. Patient with incomplete data was excluded. Data were analyzed using Chi-square analysis.
Results: Our study involved 34 patients, 21(61.8%) of them were male, and the mean age was 52.62 years (±10.77 SD). The AVF failure prevalence was 32.4% (n=11). We found no association between platelet value with AVF failure, with a p-value=0.411. There was an association between hematocrit value and AVF failure in hemodialysis patients with a p-value=0.032. Most of the patient was male and aged 45-60 with ESRD from the characteristic found.
Conclusion: There was an association between pre-operative hematocrit value and AVF failure in hemodialysis patients. There was no association between pre-operative platelet value with AVF failure.
References
2. Jennifer Reilly Lukela, Masahito Jimbo, et al. Management of Chronic Kidney Disease.UMHS Chronic Kidney Disease Guideline. 2019;1-27
3. Ali M, Ejaz A, Iram H, et al. Frequency of intradialytic complications in patients of end-stage renal disease on maintenance hemodialysis. Cureus. 2021;13(1):1-7. doi: 10.7759/cureus.12641.
4. Muhammad Satria, Raflis Rustam, Vendry Rivaldy. Hubungan Nilai Trombosit dan Hematokrit dengan Kegagalan Arteriovenous Fistula. Jurnal Kesehatan. 2020;1 1(2):1-8
5. Duque JC, Tabbara M, Martinez L, Cardona J, et al. Dialysis Arteriovenous Fistula Failure and Angioplasty: Intimal Hyperplasia and Other Causes of Access Failure. Am J Kidney Dis. 2017;69(1):147-151. doi: 10.1053/j.ajkd.2016.08.025.
6. Gjorgjievski N, Dzekova-Vidimliski P, Gerasimovska V, et al. Primary Failure of the Arteriovenous Fistula in Patients with Chronic Kidney Disease Stage 4/5. Open Access Maced J Med Sci. 2019;7(11):1782-1787. doi: 10.3889/oamjms.2019.541.
7. Mercado C, Salman L, Krishnamurthy G, et al. Early and late fistula failure. Clin Nephrol. 2008;69(2):77-83. doi: 10.5414/cnp69077.
8. Sari, N.M., Semadi, I.N., Widiana, I.G.R. Faktor - faktor risiko yang berperan terhadap terjadinya kegagalan arteriovenous fistula pada pasien gagal ginjal kronis stadium akhir di RSUP Sanglah. Medicina. 2019;50(1): 20-26
9. Satrio, R., Yasa, K.P., Widiana, I.G.R. Pengaruh kadar haemoglobin dan hematokrit dengan insiden kegagalan arteriovenous fistula pada pasien gagal ginjal kronik stadium V. Intisari Sains Medis. 2020;11(3): 978-984
10. Sarioglu O, Capar AE, Belet U. Relationship of arteriovenous fistula stenosis and thrombosis with the platelet-lymphocyte ratio in hemodialysis patients. J Vasc Access. 2020;21(5):630-635. doi: 10.1177/1129729819894113.
11. Lano G, Sallée M, Pelletier M, et al. Mean Platelet Volume Predicts Vascular Access Events in Hemodialysis Patients. J Clin Med. 2019;8(5):608. doi: 10.3390/jcm8050608.
12. Brahmbhatt A, Remuzzi A, Franzoni M, Misra S. The molecular mechanisms of hemodialysis vascular access failure. Kidney Int. 2016;89(2):303-316. doi: 10.1016/j.kint.2015.12.019.
13. Hu H, Patel S, Hanisch JJ, et al. Future research directions to improve fistula maturation and reduce access failure. Semin Vasc Surg. 2016;29(4):153-171. doi: 10.1053/j.semvascsurg.2016.08.005.
14. Esmon CT. Basic mechanisms and pathogenesis of venous thrombosis. Blood Rev. 2009;23(5):225-229. doi: 10.1016/j.blre.2009.07.002.
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Anak Agung Gede Oka Suta Wicaksana, General Practitioner, Bali Husada Cipta Canti, Denpasar, Bali, Indonesia
General Practitioner, Bali Husada Cipta Canti, Denpasar, Bali, Indonesia
I Gusti Ngurah Agung Tresna Erawan, Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine Universitas Udayana, Sanglah General Hospital, Bali, Indonesia
Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine Universitas Udayana, Sanglah General Hospital, Bali, Indonesia
Yenny Kandarini, Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine Universitas Udayana, Sanglah General Hospital, Bali, Indonesia
Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine Universitas Udayana, Sanglah General Hospital, Bali, Indonesia